Yeast mating pheromone alpha factor inhibits adenylate cyclase.
نویسندگان
چکیده
منابع مشابه
Cell fusion during yeast mating requires high levels of a-factor mating pheromone
During conjugation, two yeast cells fuse to form a single zygote. Cell fusion requires extensive remodeling of the cell wall, both to form a seal between the two cells and to remove the intervening material. The two plasma membranes then fuse to produce a continuous cytoplasm. We report the characterization of two cell fusion defective (Fus-) mutants, fus5 and fus8, isolated previously in our l...
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Conjugation in the fission yeast Schizosaccharomyces pombe is controlled by the reciprocal exchange of mating factors (for review, see [l]): M-cells (of mating type Minus) release M-factor and respond to the P-factor produced by Pcells (Plus). M-factor is a nonapeptide and has a C-terminal cysteine residue that is both carboxyl methylated and Sfarnesylated [2]. It is synthesised as a precursor ...
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The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take a brief walk down the pathway, focusing on how the signal is transmitted from the cell-surfa...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1980
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.77.4.1898